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Having said that, a similar focus of WIN although not other CB1R agonists, increases intracellular Ca2+ focus through Gq/11 protein in transfected HEK-293 cells and cultured hippocampal neurons with endogenous receptor expression [ninety three]. Furthermore, in mice hippocampal slices, CB1R expressed in astrocytes is coupled to Gq/11, raises intrac
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